Orofacial Granulomatosis Treated with Low-dose Radiation Therapy: A Case Report

We are reporting a rare chronic irritating, incapacitating condition that was controlled by low-dose radiation treatment in the case here presented. A 58 year-o ld woman had a 21⁄2-year history of painful orofacial g ranulomatosis was referred to our practice after many different treatment options failed control the disease. Presenting severe difficulty of swallowing, discomfort, labial swelling and oral ulcerations it was decided to give a trial of low-dose radiation treatment. Excellent treatment outcome was observed with significant diminution in swelling, ulceration, thickening and induration. Nine months after treatment, the patient is back to her normal self and maintains a high quality of liv ing. Low-level laser therapy may be an alternative option, however not conclusive. The experience of low-dose radiation treatment of orofacial granulomatosis has not been reported clearly in the literature, but this case may indicate it as. Therefore we would like to share this information, suggesting that low-dose radiation t reatment may be an alternative treatment for o rofacial granulomatosis, and that should be extensively exp lored both in research and clin ical trials when all other options of treatment have failed. Kewords Orofacial Granulomatosis, Radiat ion Therapy